Sten Linnarsson

Sten Linnarsson is professor of molecular systems biology at Karolinska Institutet and co-founder of the Eukaryotic Single-cell Genomics national infrastructure at SciLifeLab. He has pioneered single-cell RNA sequencing and recently completed a single-cell RNA expression atlas of the mouse nervous system.

He is also a member of the Organizing Committee of the international Human Cell Atlas Initiative.

External homepage: http://linnarssonlab.org


Key publications:

Hochgerner H, Zeisel A, Lönnerberg P, Linnarsson S. Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single cell RNA sequencing. Nature Neuroscience (2018)

Codeluppi S, Borm LE, Zeisel A, La Manno G, van Lunteren JA, Svensson CI, Linnarsson S. Spatial organization of the somatosensory cortex revealed by osmFISH. Nature Methods (2018)

Zeisel A, Hochgerner H, Lönnerberg P, Johnsson A, Memic F, van der Zwan J, Häring M, Braun E, Borm LE, La Manno G, Codeluppi S, Furlan A, Lee K, Skene N, Harris KD, Hjerling Leffler J, Arenas E, Ernfors P, Marklund U, Linnarsson SMolecular architecture of the mouse nervous system. Cell (2018)

La Manno G, Soldatov R, Zeisel A, Braun E, Hochgerner H, Petukhov V, Lidschreiber K, Kastriti ME, Lönnerberg P, Furlan A, Fan J, Borm LE, Liu Z, van Bruggen D, Guo J, He X, Barker R, Sundström E, Castelo-Branco G, Cramer P, Adameyko I, Linnarsson S and Kharchenko PV. RNA Velocity of Single Cells. Nature (2018)

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Péer D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants. The Human Cell AtlasElife (2017)

La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SRW, Enrique M, Toledo J, Villaescusa C, Lönnerberg P, Ryge J, Barker RA, Arenas E, Linnarsson SMolecular Diversity of Midbrain Development in Mouse, Human and Stem Cells. Cell (2016)

Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcão A, Xiao L, Li H, Häring M, Hochgerner H, Romanov RA, Gyllborg D, Muñoz Manchado A, La Manno G,  Lönnerberg P, Floriddia EM, Rezayee F, Ernfors P, Arenas E, Hjerling J, Leffler T, Harkany, Richardson WD, Linnarsson S, Castelo-Branco G. Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous systemScience (2016)

Zeisel A, Munoz Manchado A, Codeluppi S, Lönnerberg P, La Manno G, Juréus A, Marques S, Munguba H, He L, Betsholtz C, Rolny C, Castelo-Branco G, Hjerling-Leffler J, Linnarsson S. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq. Science (2015)