Mats Nilsson is professor of biochemistry/molecular diagnostics at Stockholm University and SciLifeLab, and has developed in situ RNA sequencing, which reveals spatial patterns of gene expression with single-cell resolution.
Mats Nilsson is also the Site Director for SciLifeLab in Stockholm.
Lab webpage: https://nilssonlab.org/people/mats-nilsson/
Key publications:
Soares RRG, Madaboosi N, Nilsson M. Rolling Circle Amplification in Integrated Microsystems: An Uncut Gem toward Massively Multiplexed Pathogen Diagnostics and Genotyping.
Accounts of chemical research (Oct 2021)
Haniffa M, Taylor D, Linnarsson S, Aronow BJ, Bader GD, Barker RA, Camara PG, Camp JG, Chédotal A, Copp A, Etchevers HC, Giacobini P, Göttgens B, Guo G, Hupalowska A, James KR, Kirby E, Kriegstein A, Lundeberg J, Marioni JC, Meyer KB, Niakan KK, Nilsson M, Olabi B, Pe’er D, Regev A, Rood J, Rozenblatt-Rosen O, Satija R, Teichmann SA, Treutlein B, Vento-Tormo R, Webb S, Human Cell Atlas Developmental Biological Network . A roadmap for the Human Developmental Cell Atlas.
Nature (Sep 2021)
La Manno G, Siletti K, Furlan A, Gyllborg D, Vinsland E, Mossi Albiach A, Mattsson Langseth C, Khven I, Lederer AR, Dratva LM, Johnsson A, Nilsson M, Lönnerberg P, Linnarsson S. Molecular architecture of the developing mouse brain.
Nature (Jul 2021)
Chang KY, Riley WJ, Knox SH, Jackson RB, McNicol G, Poulter B, Aurela M, Baldocchi D, Bansal S, Bohrer G, Campbell DI, Cescatti A, Chu H, Delwiche KB, Desai AR, Euskirchen E, Friborg T, Goeckede M, Helbig M, Hemes KS, Hirano T, Iwata H, Kang M, Keenan T, Krauss KW, Lohila A, Mammarella I, Mitra B, Miyata A, Nilsson MB, Noormets A, Oechel WC, Papale D, Peichl M, Reba ML, Rinne J, Runkle BRK, Ryu Y, Sachs T, Schäfer KVR, Schmid HP, Shurpali N, Sonnentag O, Tang ACI, Torn MS, Trotta C, Tuittila ES, Ueyama M, Vargas R, Vesala T, Windham-Myers L, Zhang Z, Zona D. Substantial hysteresis in emergent temperature sensitivity of global wetland CH4 emissions.
Nature communications (Apr 2021)
Floriddia EM, Lourenço T, Zhang S, van Bruggen D, Hilscher MM, Kukanja P, Gonçalves Dos Santos JP, Altınkök M, Yokota C, Llorens-Bobadilla E, Mulinyawe SB, Grãos M, Sun LO, Frisén J, Nilsson M, Castelo-Branco G. Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury.
Nature communications (Nov 2020)
Järveoja J, Nilsson MB, Crill PM, Peichl M. Bimodal diel pattern in peatland ecosystem respiration rebuts uniform temperature response.
Nature communications (Aug 2020)
Asp M, Giacomello S, Larsson L, Wu C, Fürth D, Qian X, Wärdell E, Custodio J, Reimegård J, Salmén F, Österholm C, Ståhl PL, Sundström E, Åkesson E, Bergmann O, Bienko M, Månsson-Broberg A, Nilsson M, Sylvén C, Lundeberg J. A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.
Cell (Dec 2019)
Qian X, Harris KD, Hauling T, Nicoloutsopoulos D, Muñoz-Manchado AB, Skene N, Hjerling-Leffler J, Nilsson M. Probabilistic cell typing enables fine mapping of closely related cell types in situ.
Nature methods (Nov 2019)
Wu D, Yan J, Shen X, Sun Y, Thulin M, Cai Y, Wik L, Shen Q, Oelrich J, Qian X, Dubois KL, Ronquist KG, Nilsson M, Landegren U, Kamali-Moghaddam M. Profiling surface proteins on individual exosomes using a proximity barcoding assay.
Nature communications (Aug 2019)
Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I. Spatiotemporal structure of cell fate decisions in murine neural crest.
Science (New York, N.Y.) (Jun 2019)
Carow B, Hauling T, Qian X, Kramnik I, Nilsson M, Rottenberg ME. Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma.
Nature communications (Apr 2019)
Tiklová K, Björklund ÅK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmström F, Joodmardi E, Nilsson M, Parmar M, Perlmann T. Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development.
Nature communications (Feb 2019)
Segura JH, Nilsson MB, Haei M, Sparrman T, Mikkola JP, Gräsvik J, Schleucher J, Öquist MG. Microbial mineralization of cellulose in frozen soils.
Nature communications (Oct 2017)
Schütte M, Risch T, Abdavi-Azar N, Boehnke K, Schumacher D, Keil M, Yildiriman R, Jandrasits C, Borodina T, Amstislavskiy V, Worth CL, Schweiger C, Liebs S, Lange M, Warnatz HJ, Butcher LM, Barrett JE, Sultan M, Wierling C, Golob-Schwarzl N, Lax S, Uranitsch S, Becker M, Welte Y, Regan JL, Silvestrov M, Kehler I, Fusi A, Kessler T, Herwig R, Landegren U, Wienke D, Nilsson M, Velasco JA, Garin-Chesa P, Reinhard C, Beck S, Schäfer R, Regenbrecht CR, Henderson D, Lange B, Haybaeck J, Keilholz U, Hoffmann J, Lehrach H, Yaspo ML. Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nature communications (Feb 2017)
Jonsson S, Andersson A, Nilsson MB, Skyllberg U, Lundberg E, Schaefer JK, Åkerblom S, Björn E. Terrestrial discharges mediate trophic shifts and enhance methylmercury accumulation in estuarine biota.
Science advances (Feb 2017)
Kühnemund M, Wei Q, Darai E, Wang Y, Hernández-Neuta I, Yang Z, Tseng D, Ahlford A, Mathot L, Sjöblom T, Ozcan A, Nilsson M. Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy.
Nature communications (Jan 2017)
Mezger A, Fock J, Antunes P, Østerberg FW, Boisen A, Nilsson M, Hansen MF, Ahlford A, Donolato M. Scalable DNA-Based Magnetic Nanoparticle Agglutination Assay for Bacterial Detection in Patient Samples.
ACS nano (Jul 2015)
Jonsson S, Skyllberg U, Nilsson MB, Lundberg E, Andersson A, Björn E. Differentiated availability of geochemical mercury pools controls methylmercury levels in estuarine sediment and biota.
Nature communications (Aug 2014)
Russell C, Welch K, Jarvius J, Cai Y, Brucas R, Nikolajeff F, Svedlindh P, Nilsson M. Gold nanowire based electrical DNA detection using rolling circle amplification.
ACS nano (Jan 2014)
Ke R, Mignardi M, Pacureanu A, Svedlund J, Botling J, Wählby C, Nilsson M. In situ sequencing for RNA analysis in preserved tissue and cells.
Nature methods (Jul 2013)
Willers SM, Eriksson C, Gidhagen L, Nilsson ME, Pershagen G, Bellander T. Fine and coarse particulate air pollution in relation to respiratory health in Sweden.
The European respiratory journal (Jan 2013)
Larsson C, Grundberg I, Söderberg O, Nilsson M. In situ detection and genotyping of individual mRNA molecules.
Nature methods (Apr 2010)